LPCAT1 antibody

Catalog No. ABIN7115971

This Mouse Monoclonal antibody specifically detects LPCAT1 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for LPCAT1 antibody (ABIN7115971)

Target: LPCAT1 (Lysophosphatidylcholine Acyltransferase 1 (LPCAT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LPCAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 7E4

Product Details anti-LPCAT1 Antibody

Purpose: LPCAT1 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: lysophosphatidylcholine acyltransferase 1

Isotype: IgG2a

Application Details

Application Notes: WB: 1:5000-1:50000, IHC: 1:50-1:500, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for LPCAT1

Target: LPCAT1 (Lysophosphatidylcholine Acyltransferase 1 (LPCAT1))

Alternative Name: LPCAT1

Background:

Synonyms: Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1, LPCAT-1, LysoPC acyltransferase 1)|1-acylglycerol-3-phosphate O-acyltransferase|1-acylglycerophosphocholine O-acyltransferase|1-alkenylglycerophosphocholine O-acyltransferase|1-alkylglycerophosphocholine O-acetyltransferase|Acetyl-CoA:lyso-platelet-activating factor acetyltransferase (Acetyl-CoA:lyso-PAF acetyltransferase, Lyso-PAF acetyltransferase, LysoPAFAT)|Acyltransferase-like 2|Phosphonoformate immuno-associated protein 3|LPCAT1|AYTL2|PFAAP3

Background: Possesses both acyltransferase and acetyltransferase activities(PubMed:16864775, PubMed:21498505). Activity is calcium-independent(By similarity). Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine(LPC) into phosphatidylcholine(PC)(PubMed:21498505). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively(PubMed:16704971). May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology(PubMed:16864775). Involved in the regulation of lipid droplet number and size(PubMed:25491198).

Molecular Weight: 55 kDa

Gene ID: 79888

UniProt: Q8NF37